Dr Gabriela Eppel

BSc (Hons) (Monash), PhD (Monash)

Research Officer - Department of Physiology

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Dr Gabriela Eppel completed a PhD in the Department of Biochemistry, Monash University.  Gabriela's PhD project investigated the renal filtration and reabsorption of albumin in health and disease, and also the limitations of techniques used to measure urinary albumin excretion.  In 2001, Gabriela commenced working as a Post-doctoral Research Officer in the Department of Physiology.  Her research here has focussed on the control of renal medullary blood flow, which plays a significant role in the long-term control of blood pressure, and in the development of hypertension.  One of her main interests is in the influence of the renal nerves on medullary blood flow.

Publications

1. Evans RG,Eppel GA, Anderson WP, Denton KM. Mechanisms underlying the differential control of blood flow in the renal medulla and cortex. Am J Hypertens 22: 1439-51, 2004. [Review]
2. Eppel GA, Lee LL, Evans RG. a-Adrenoceptor subtypes mediating regional kidney blood flow responses to renal nerve stimulation. Auton Neurosci 112: 15-24, 2004.
3. Eppel GA, Malpas SC, Denton KM, Evans RG. Neural control of renal medullary perfusion.Clin Exp Pharmacol Physiol, 31: 387-96, 2004. [Symposium Review]
4. Guild SJ, Malpas SC, Eppel GA, Nguang SK, Evans RG. Effect of renal perfusion pressure on the neural regulation of intrarenal blood flow in rabbits. Clin Exp Pharmacol Physiol 31: 35-45, 2004.
5. Eppel GA, Denton KM, Malpas SC, Evans RG. Nitric oxide in responses of regional kidney perfusion to renal nerve stimulation and renal ischaemia. Pflügers Arch - Eur J Physiol 447: 205-213, 2003.
6. Oliver JJ, Eppel GA, Rajapakse NW, Evans RG. Lipoxygenase and cyclooxygenase products in control of regional kidney blood flow in rabbits. Clin Exp Pharmacol Physiol 30:812-819, 2003.
7. Duke LM, Eppel GA, Widdop RE, Evans RG. Disparate roles of AT2-receptors in the renal cortical and medullary circulations of anaesthetized rabbits. Hypertension 42: 200-205, 2003
8. Eppel GA, Bergström G, Anderson WP, and Evans RG. Autoregulation of renal medullary blood flow in rabbits. Am J Physiol Reg Int Comp Physiol 284: R233-44, 2003.
9. Kalyan A, Eppel GA, Anderson WP, Oliver JJ, Evans RG. Renal medullary interstitial infusion is a flawed technique for examining vasodilator mechanisms in anaesthetized rabbits. J Pharmacol Tox Meth 47: 153-159, 2002.
10. Guild SJ, Eppel GA, Malpas SC, Rajapakse NW, Stewart A, and Evans RG. Regional responsiveness of renal perfusion to activation of the renal nerves. Am J Physiol Reg Int Comp Physiol 283: R1177-86, 2002.
11. Eppel GA, Pratt LM, Greive KA, and Comper WD. Exogenous albumin peptides influence the processing of albumin during renal passage. Nephron 92: 156-64, 2002.
12. Eppel GA, Pratt LM, Greive KA, and Comper WD. Exogenous albumin peptides influence the processing of albumin during renal passage. Nephron 92: 156-64, 2002.
13. Greive KA, Eppel GA, Reeve S, Smith AI, Jerums G, and Comper WD. Immuno-unreactive albumin excretion increases in streptozotocin diabetic rats. Am J Kidney Dis 38: 144-152, 2001.
14. Eppel GA, Osicka TM, Pratt LM, Jablonski P, Howden B, Glasgow EF, and Comper WD. The return of glomerular filtered albumin to the rat renal vein - The albumin retrieval pathway. Ren Fail 23: 347-363, 2001.
15. Eppel GA, Nagy S, Jenkins MA, Tudball RN, Daskalakis M, Balazs NDH, and Comper WD. Variability of standard clinical protein assays in the analysis of a model urine solution of fragmented albumin. Clin Biochem 33: 487-494, 2000.
16. Eppel GA, Takazoe K, Nikolic-Paterson DJ, Lan HY, Atkins RC, and Comper WD. Characteristics of albumin processing during renal passage in anti-Thy1 and anti-glomerular basement membrane glomerulonephritis. Am J Kidney Dis 35: 418-426, 2000.
17. Eppel GA, Osicka TM, Pratt LM, Jablonski P, Howden BO, Glasgow EF, and Comper WD. The return of glomerular-filtered albumin to the rat renal vein. Kidney Int 55: 1861-1870, 1999.

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